Due to ongoing parts shortage issues impacting global production, the availability of some equipment, options or features may be limited. Please contact your local Audi Dealer for more information, and be sure to verify the vehicle you purchase includes all expected features and equipment. Thank you for your patience as we work to navigate these limitations.
2022 Audi Q5 vs. 2022 Lexus RX 350
Are you searching for the ideal blend of premium luxury, sporty good looks, and the latest tech features? The 2022 Audi Q5 is a solid choice from the Audi SUV family lineup. But how does it compare to other SUVs in the luxury SUV marketplace? The team at Audi Northwest Indiana takes a look at this spirited performer alongside the 2022 Lexus RX 350 in this review.
Learn about the similarities and differences in key areas, and if you determine that the 2022 Audi Q5 is right for you, search our inventory and contact us at (888) 454-9767 or visit our showroom to set up a test drive. View our hours and directions to plan your visit.
The 2022 Audi Q5 has a starting MSRP of $43,300, while the 2022 Lexus RX 350 starts at $46,645 MSRP.

2022 Audi Q5 vs. 2022 Lexus RX 350 Performance Specs
The 2022 Audi Q5 added another engine early in 2022 to expand the offerings to three distinct ― yet powerful ― options. Choose between a turbocharged gas-powered engine with or without mild hybrid technology (MHEV) as well as a plug-in hybrid option that features a 17.9 kilowatt-hour battery.
All trims offered on the 2022 Lexus RX 350 come equipped with the same gas-powered V6.
2022 Audi Q5
Engine | Horsepower | Torque | MPG |
---|---|---|---|
40 TFSI® quattro® S tronic® | 201 HP | 236 lb.-ft. | 23 city/29 hwy |
45 TFSI® quattro® S tronic® with MHEV technology | 261 HP | 273 lb.-ft. | 23 city/28 hwy |
55 TFSI® e Plug-in hybrid (PHEV) | 362 HP | 369 lb.-ft. | 61 MPGe (combined), 390 miles total driving range/23 miles (electric only) |
2022 Lexus RX 350
Engine | Horsepower | Torque | MPG |
---|---|---|---|
3.5L 24V VVT-iW V6 | 295 HP | 268 lb.-ft. | 20 city/27 hwy MPG |
2022 Audi Q5 vs. 2022 Lexus RX 350 Interior & Cargo Space
When it comes to stowing luggage or other necessities, the 2022 Audi Q5 provides 25.85 cubic feet behind the rear seat, which is expandable to 54 cubic feet when you fold the rear seats down. In comparison, the 2022 Lexus RX 350 provides 16 cubic feet behind the second-row seat and 32.7 cubic feet when the second-row seats are folded down.
Among the interior features the 2022 Audi Q5 and 2022 Lexus RX 350 share are:
- Panoramic sunroof
- Heated and ventilated front seats
- Leather seating surfaces
- Heated second-row seats with 40/20/40 split folds and adjustable recline
- Leather-wrapped heated steering wheel with a power tilt and telescopic adjustable steering column
- Power tailgate
- LED interior lighting
- Illuminated door sills
Unique to the Audi Q5 are brown walnut wood inlays; the Lexus RX 350 offers matte bamboo, open-pore brown or black walnut, scored aluminum, or gray sapele wood with aluminum trim. The RX 350 also offers NuLuxe® seating material.

2022 Audi Q5 vs. 2022 Lexus RX 350 Dimensions
With two rows of seating, the 2022 Audi Q5 and 2022 Lexus RX 350 can comfortably seat five people. Compare interior dimensions in the chart below.
2022 Lexus RX 350 | Model | 2022 Audi Q5 |
---|---|---|
5 | Seating Capacity | 5 |
44.1 in. | Front Legroom | 40.9 in. |
38 in. | Rear Legroom | 38 in. |
39.4 in. | Front Headroom | 39.5 in. |
39.1 in. | Rear Headroom | 39.3 in. |

2022 Audi Q5 vs. 2022 Lexus RX 350 Technology Features
Among the tech features the 2022 Audi Q5 and 2022 Lexus RX 350 share are a multimedia system with navigation, 4G LTE Wi-Fi® hotspot, Bluetooth®, SiriusXM® Satellite Radio, Apple CarPlay® and Android Auto™ compatibility, wireless charging, three-zone automatic climate control, and smartphone connectivity.
Unique to the Audi Q5:
- Audi virtual cockpit or Audi virtual cockpit plus
- 10.1-in. display with touch response
- Audi connect® CARE assistance and security services
- Audi phone box with signal booster
- Audi sound system or Bang & Olufsen® sound system with 3D sound
The Lexus RX 350 also features:
- 12-3.-in. display with voice command
- Nine- or 12-speaker premium audio system
- HD Radio™
- Lexus Enform Remote connected app
- Alexa compatibility
2022 Audi Q5 vs. 2022 Lexus RX 350 Safety
Both luxury SUVs leverage advanced safety features and driver assist tech to help protect and support you when you’re on the road.
2022 Audi Q5
- Top view camera system with Virtual 360 view
- Head-up display with traffic sign recognition
- Audi pre sense® sensor technology
- Park assist
- Audi side assist
- Audi active lane assist
- Adaptive cruise control with Traffic Jam assist
- Lane departure warning
2022 Lexus RX 350
- Head-up display
- Pre-collision system with pedestrian detection, lane tracing assist, and lane departure alert with steering assist
- Road sign assist
- All-speed dynamic radar cruise control
- Panoramic view monitor and intuitive parking assist with auto braking and rear cross-traffic braking
2022 Audi Q5 for Sale Near Me
Audi Northwest Indiana is conveniently located near Crown Point, Schererville, Valparaiso, Hammond, and St. John.
